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	NR-10503 Variola Major Virus (India-1967) A36R Protein, Recombinant from Baculovirus (Homolog of Vaccinia Virus A33R) (Proteins)

Description:	Variola Major Virus (India-1967) A36R Protein, Recombinant from Baculovirus (Homolog of Vaccinia Virus A33R)
Organism:	Variola major virus
Biosafety Level:	1
Availability Status:	In Stock
Store at:	-20°C or colder
Contributor:	GH Cohen, RJ Eisenberg
Comments:	Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment. NR-10503 is a recombinant form of the variola major (India-1967) A36R protein, a homolog of the vaccinia virus (WR) A33R protein. The full-length variola major virus A36R protein contains 184 amino acid residues (GenPept: NP_042184; GenBank: X69198). NR-10503 is a truncated form of A36R, comprising amino acid residues 58-184, and lacking the N-terminal transmembrane domain of the intact protein. NR-10503 was produced by baculovirus infection of Trichoplusia ni insect larvae using the proprietary Chesapeake PERL technology, PERLXpress. The protein was purified using standard chromatographic methods. NR-10503 was demonstrated to be functionally active based on its reactivity with an anti-variola major virus A36R rabbit polyclonal antibody (R-213 provided by G. H. Cohen and R. J. Eisenberg). Each vial contains approximately 1 mg of NR-10503 in 30 mM phosphate buffer (pH 7.6) containing 50 mM KCl, 100 mM NaCl and 0.05% polysorbate (v/v).
Citations:	Acknowledgment for publications should read "The following reagent was obtained through the NIH Biodefense and Emerging Infections Research Resources Repository, NIAID, NIH: Variola Major Virus (India-1967) A36R Protein, Recombinant from Baculovirus, NR-10503."

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