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Publications

Agnihothram SS, York J, Trahey M, Nunberg JH. Bitopic Membrane Toplogy of the Stable Signal Peptide in the Tripartite Junin Virus GP-C Envelope Glycoprotein Complex. J Virol. 2007 Apr; 81(8):4331-7. Epub 2007 Jan 31. PMID: 17267484

Agnihothram SS, York J, Trahey M, Nunberg JH. Role of the Stable Signal Peptide and Cytoplasmic Domain of G2 in Regulating Intracellular Transport of the Junin Virus Envelope Glycoprotein Complex. J Virol. 2006 June; 80(11):5189-98. PMIDDD: 16698999
 
Akiko Kikuchi-Maki, Tracey L. Catina and Kerry S. Campbell. Cutting Edge: KIR2DL4 Transduces Signals into Human NK Cells through Association with the Fc Receptor y Protein. The Journal of Immunology, 2005, 174:3859-3863. 

Brahmbhatt, T.N., B.K. Janes, E.S. Stibitz, S.C. Darnell, P. Sanz, S.B. Rasmussen, and A.D. O’Brien. 2007. Bacillus anthracis exosporium protein BclA affects spore germination, interaction with extracellular matrix proteins, and hydrophobicity. Infect. Immun. 75:5233-5239. PubMed Central ID: PMC2168272

Brahmbhatt, T.N., S.C. Darnell, H.M. Carvalho, P. Sanz, T.J. Kang, R.L. Bull, S.B. Rasmussen, A.S. Cross, and A.D. O’Brien. 2007. Recombinant exosporium protein BclA of Bacillus anthracis is effective as a booster for mice primed with suboptimal amounts of protective antigen. Infect. Immun. 75:5240-5247. PubMed Central ID: PMC2168312

Brusic V, August JT. The Changing Field of Vaccine Development in the Genomics  
     Era. Pharmacogenomics 5, 597-600, 2004.
 
Brusic, V, August, JT, and Petrovsky, N, Information Technologies for Vaccine  
     Research, Expert Rev. Vaccines 4, 407-417, 2005.
 
Butt TR, Edavettal S, Hall J and Mattern M R. (2005) SUMO Fusion Technology for Difficult to Express Proteins. Protein Expression and Purification 43:1-9.

Chen N, Li G, Liszewski MK, Atkinson JP, Jahrling PB, Feng Z, Schriewer J, Buck C, Wang C, Lefkowitz EJ, Esposito JJ, Harms T, Damon IK, Roper RL, Upton C, Buller RM. Virulence Differences between Monkeypox Virus Isolates from West Africa and the Congo Basin. Virology. 2005 Sep 15; 340(1):46-63.

Cheng H, Ito N, Tseng C, Makino, S. Severe Acute Respiratory Syndrome Coronavirus 7a Accessory Protein Is a Viral Structural Protein. J. Virol. 2006 Aug; 80(15):7267-7294.

Yingying Chen, Bice Perussia and Kerry S. Campbell, Prostaglandin D2 Suppresses Human NK Cell Function via Signaling through D Prostanoid Receptor; The Journal of Immunology, 2007, 179:2766-2773. 

Comer JE, Chopra AK, Peterson JW, Konig R. Direct Inhibition of T-Lymphocyte Activation by Anthrax Toxins In Vivo. Infection and Immunity. December 2005; 73(12): 8275-8281.

Comer JE, Galindo CL, Zhang Fan, Wenglikowski AM, Bush KL, Garner HR, Peterson JW, Copra AK. Murine Macrophage Transcriptional and Functional Responses to Bacillus Anthracis Edema Toxin. Microbial Pathog. (in press); 2006.

Comer JE, Noffsinger DM, McHenry DJ, Weisbaum DM, Chatuev GM, Chopra AK, Peterson JW. Evaluation of the Protective Effects of Quinacrine Against Bacillus Anthracis AMES.
J Toxicology and Environmental Health, Part A, 2006; 69:1083-1095.
 
Gupta V, Tabiin TM, Sun K, Chandrasekaran A, Anwar A, Yang K, Chikhlikar P, Salmon J, Brusic V, Marques ETA, Srinivasan KN, and August JT,  SARS Coronavirus Nucleocapsid Immunodominant T-cell Epitopes are Common to Both Exogenous Recombinant and Endogenous DNA Encoded Immunogens. Virology, 347: 127-139, 2006.
 
Gupta V, Tabiin TM, Sun K, Chandrasekaran A, Anwar A, Yang K, Chikhlikar P, Salmon J, Brusic V, Marques ETA, Srinivasan KN, and August JT.  SARS Coronavirus Nucleocapsid Immunodominant T-cell Epitopes are Common to Both Exogenous Recombinant and Endogenous DNA Encoded Immunogens. Virology, 347,127-139, 2006
 
Han DP, Penn-Nicholson A, Cho MW. Identification of Critical Determinants on ACE2 for SARS-CoV Entry and Development of a Potent Entry Inhibitor. Virology. 2006; 350:15-25.

JF Kuhn, P Hoerth, ST Hoehn, T Preckel, KB Tomer. Proteomics Study of Anthrax Lethal Toxin-treated Murine Macrophages. Electrophoresis. 2006 Apr; 27(8):1584-97.

Khan AM, Miotto O, Heiny AT, Salmon J, Srinivasan KN, Nascimento E, Marques ET, Brusic V, Wee Tan T, August JA. A Systematic Bioinformatics Approach for Selection of Epitope-based Vaccine Targets. Cellular Immunology, 2007 (in press).

Lanteri, MC, Heitman JW, Owen RE, Busch TA, Gefter N, Kiely N, Kamel HT, Tobler LH, Busch MP, and Norris PJ. Comprehensive analysis of West Nile virus T cell responses in human infection. JID May 1;197(9):1296-1306 (2008).

Laughlin, EM, Miller, JD, James E, Fillos, Dimitry, Ibegbu, CC, Mittler, R, Akondy, R, Kwok, William, Ahmed R, and Nepom G. (2006). Antigen-Specific CD4+T Cells Recognize Epitopes of Protective Antigen Following AVA Vaccination. Infection and Immunology, submitted for publication.

Lee J-S, Poo H, Han DP, Hong S-P, Kim K, Cho MW, Kim E, Sung M-H, Kim C-J. Mucosal Immunization with Surface-displayed SARS Coronavirus Spike Protein on Lactobacillus Casei Induces Neutralizing Antibodies in Mice. J. Virol. 2006; 80:4079-4087.

Lixin Xu, Hui Fang, and David M. Frucht. (2008) Anthrax Lethal Toxin Increases Superoxide Production Capacity in Murine Neutrophils via Differential Effects on MAPK Signaling Pathways. Journal of Immunology 180:4139.

Marblestone J, Edavettal S, Lim Y, Lim, P, Zuo, X, Butt TR. (2006) Comparison of SUMO Fusion Technology with Traditional Gene Fusion System: Effects of Recombinant Protein Expression and Purification. Protein Science 15:182-189.

McLachlan J.B., C.P. Shelburne, J.P. Hart, S.V. Pizzo, R. Goyal, R. Brooking, H. F. Staats and S. N. Abraham.  A Novel Class of Mucosal Vaccine Adjuvants that Exploit the Immunoregulatory Functions of Mast Cells.  Nature Medicine 14:536-541, 2008.

Peterson JW, Comer JE, Noffsinger DM, Wenglikowski A, Walberg KG, Chatuev BM, Chopra AK, Stanberry LR, Kang AS, Scholz WW, Sircar J. Human Monoclonal Anti-protective Antigen Antibody Completely Protects Rabbits and is Synergistic with Ciprofloxacin in Protecting Mice and Guinea Pigs Against Inhalation Anthrax. Infect Immun. 2006 Feb; 74(2): 1016-24.

Purtha WE, Myers N, Mitaksov V., Sitati E., Connolly J, Fremont DH, Hansen TR, Diamond MS. Antigen-specific Cytotoxic T Lymphocytes Protect Against Lethal West Nile Virus Encephalitis. Eur J Immunol. 2007 July; 37(7):1845-54. PMID: 17559174 

Sanz, P., L.D. Teel, F. Alem, H.M.Carvalho, S.C. Darnell, and A.D. O’Brien. 2008. Detection of Bacillus anthracis spore germination in vivo by bioluminescence imaging. Infect Immun. 76:1036-1047. PubMed ID: 18195028

Sapra R, Gaucher SP, Lachmann JS, Buffleben GM, Chirica GS, Comer JE, Peterson JW, ChopraAK, SinghAK. Proteomic Analyses of Murine Macrophages Treated with Bacillus anthracis Lethal Toxin. Microb Pathog. 2006 Oct-Nov; 41(4-5):157-67. Epub 2006 Sep 1.

Roti M, Yang J, Berger D, Huston L, James EA, Kwok WW. Healthy human subjects have CD4+ T cells directed against H5N1 influenza virus. J Immunol. 2008 Feb 1;180(3):1758-68. PMID: 18209073 [PubMed - indexed for MEDLINE]

Shaker DS, BR Sloat, UM Le, CV Löhr, N Yanasarn, KA Fischer, ZR Cui, Immunization by application of DNA vaccine onto a skin area wherein the hair follicles have been induced into anagen-onset stage. Mol. Ther. (2007) 15 (11): 2037-43.
 
Sitati EM, Diamond MS. CD$+ T-cell Responses are Required for Clearance of West Nile Virus from the Central Nervous System. J Virol. 2006 Dec; 80(24):12060-9. Epub 2006 Octo 11. PMID: 17035323

Sloat BR, DS Shaker, UM Le, ZR Cui, Nasal immunization with the mixture of PA63, LF, and a PGA conjugate induced strong antibody responses against all three antigens. FEMS Immunol. Med. Microbiol. (2008) 52(2):169-179. 

Smith ME, Koser M, Xiao S, Siler C, McGettigan JP, Calkins C, Pomerantz RJ, Dietzschold B, Schnell MJ. Rabies Virus Glycoprotein as a Carrier for Anthrax Protective Antigen. ScienceDirect. July 2006; Virology 353:344-356.Srinivasan KN, Brusic V and August JT. New Technologies for Vaccine Development. Drug Dev Res, 62:387-396, 2004.

Staats, H.F., S. M.  Alam, R. M. Scearce, S. M. Kirwan, J. X. Zhang, W. M. Gwinn and B. F. Haynes.  In vitro and In vivo Characterization of Anthrax Anti-Protective Antigen and Anti-Lethal Factor Monoclonal Antibodies After Passive Transfer in a Mouse Lethal Toxin Challenge Model to Define Correlates of Immunity.  Infection and Immunity, 75: 5443-5452, 2007.

Treanor JJ, Campbell JD, Zangwill KM, Rowe T, Wolff M. Evaluation of the Safety and Immunogenicity of an Inactivated Subvirion H5N1 Influenza Virus Vaccine in Humans. NEJOM. 2006; 354:1343-51.
 
York J, Nunberg JH. A novel zinc-binding domain is essential for formation of the functional Junín virus envelope glycoprotein complex. J Virol. 2007 Dec;81(24):13385-91. Epub 2007 Oct 10. PMID: 17928348 [PubMed - indexed for MEDLINE]

York J, Nunberg JH. Lins Abstract Distinct Requirements for Signal Peptidase Processing and Function in the Stable Signal Peptide Subunit of the Junin Virus Envelope Glycoprotein. Virology. 2007 Mar 1; 359(1):72-81. Epub 2006 Oct 12.

York J, Nunberg JH. Linds Free in PMC Role of the Stable Signal Peptide of Junin Arenavirus Envelope Glycoprotein in pH-dependent Membrane Fusion. J Virol. 2006 Aug; 80(15):7775-80. PMID: 16840359 [PubMed – indexed for MEDLINE]
 
Zuo Xun, Mattern MR, Tan R, Li S, Hall H, Sterner DE, Shoo J, Lim P, Sarafianos SG, Kazi  L, Navas-Martin, Weiss SR and Butt, T. R. (2005) Expression and Purification of SARS Coronavirus Proteins Using SUMO-Fusions. Protein Expression and Purification 42:100-110.
 
Zuo Xun, Li Shuisen, Hall John, Mattern Michael R, Tran Tran, Shoo Joshua, Tan Robin., Weiss Susan and Butt TR.(2005) Enhanced Expression and Purification of Membrane Proteins by SUMO Fusion in Echerichia Coli. J Structural and Functional Genomics 6:103-111.