TARGET Research Results
Details
DescriptionTREHALOSE SYNTHASE TRES
Accession numberRv0126
Gene nametreS
Gene length1806
Protein length601
Coordinates152324..154129
Orientation+
Molecular mass68592.83
Isoelectric point4.58

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU0126-478[no data]
JHU0126-518[no data]
JHU0126-1061[no data]
 

CDC1551 Homolog
ORFMT0134
Essentiality Prediction
Sassetti et al, 2003*slow grower / non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU0126-478MT0134Rv01264781806no (will be available later)
JHU0126-1061MT0134Rv012610611806yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]