TARGET Research Results
Details
DescriptionCONSERVED HYPOTHETICAL PROTEIN
Accession numberRv0443
Gene nameRv0443
Gene length516
Protein length171
Coordinates532396..532911
Orientation+
Molecular mass18958.22
Isoelectric point5.2

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU0443-218[no data]
JHU0443-287Not-Attenuated
JHU0443-374[no data]
JHU0443-218[no data]
 

CDC1551 Homolog
ORFMT0459
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU0443-218MT0459Rv0443218558no (will be available later)
JHU0443-374MT0459Rv0443374558yes
JHU0443-218MT0459Rv0443218558yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]