TARGET Research Results
Details
DescriptionPOSSIBLE HEMOLYSIN-LIKE PROTEIN
Accession numberRv1085c
Gene nameRv1085c
Gene length729
Protein length242
Coordinates1209756..1210484
Orientation-
Molecular mass26034.39
Isoelectric point9.86

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1085c-521[no data]
JHU1085c-128[no data]
JHU1085c-262[no data]
 

CDC1551 Homolog
ORFMT1117
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1085c-521MT1117Rv1085c521729yes
JHU1085c-128MT1117Rv1085c128729yes
JHU1085c-262MT1117Rv1085c262729no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]