TARGET Research Results
Details
DescriptionProbable catechol-o-methyltransferase
Accession numberRv1703c
Gene nameRv1703c
Gene length591
Protein length196
Coordinates1929131..1929721
Orientation-
Molecular mass21537.42
Isoelectric point5.94

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1703c-595[no data]
JHU1703c-241[no data]
JHU1703c-341[no data]
 

CDC1551 Homolog
ORFMT1743
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1703c-595MT1743Rv1703c595702yes
JHU1703c-241MT1743Rv1703c241702yes
JHU1703c-341MT1743Rv1703c341702no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]