TARGET Research Results
Details
DescriptionProbable conserved integral membrane protein
Accession numberRv2209
Gene nameRv2209
Gene length1539
Protein length512
Coordinates2473400..2474938
Orientation+
Molecular mass53578.81
Isoelectric point11.63

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2209-1465[no data]
JHU2209-712[no data]
JHU2209-662[no data]
JHU2209-537[no data]
JHU2209-722[no data]
 

CDC1551 Homolog
ORFMT2265
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2209-712MT2265Rv22097121539yes
JHU2209-662MT2265Rv22096621539yes
JHU2209-722MT2265Rv22097221539no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]