TARGET Research Results
Details
DescriptionPOSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
Accession numberRv2345
Gene nameRv2345
Gene length1983
Protein length660
Coordinates2623821..2625803
Orientation+
Molecular mass70029.54
Isoelectric point8.71

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2345-1979[no data]
JHU2345-282Not-Attenuated
JHU2345-283[no data]
JHU2345-614[no data]
 

CDC1551 Homolog
ORFMT2410
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2345-1979MT2410Rv234519791983yes
JHU2345-283MT2410Rv23452831983no (will be available later)
JHU2345-614MT2410Rv23456141983yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]