TARGET Research Results
Details
DescriptionPROBABLE GTP-BINDING PROTEIN HFLX
Accession numberRv2725c
Gene namehflX
Gene length1488
Protein length495
Coordinates3037427..3038914
Orientation-
Molecular mass53327.51
Isoelectric point6.81

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2725c-495[no data]
JHU2725c-64[no data]
JHU2725c-365[no data]
 

CDC1551 Homolog
ORFMT2797
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2725c-495MT2797Rv2725c4951671yes
JHU2725c-64MT2797Rv2725c641671no (will be available later)
JHU2725c-365MT2797Rv2725c3651671no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]