TARGET Research Results
Details
DescriptionPOSSIBLE PENICILLIN-BINDING LIPOPROTEIN
Accession numberRv2864c
Gene nameRv2864c
Gene length1812
Protein length603
Coordinates3175454..3177265
Orientation-
Molecular mass63014.17
Isoelectric point5.74

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2864c-1115[no data]
JHU2864c-1367[no data]
JHU2864c-1856[no data]
JHU2864c-548[no data]
JHU2864c-546[no data]
JHU2864c-1242Not-Attenuated
 

CDC1551 Homolog
ORFMT2933
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2864c-1115MT2933Rv2864c11151857no (will be available later)
JHU2864c-548MT2933Rv2864c5481857yes
JHU2864c-546MT2933Rv2864c5461857yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]