TARGET Research Results
Details
DescriptionPROBABLE ESTERASE/LIPASE LIPF
Accession numberRv3487c
Gene namelipF
Gene length834
Protein length277
Coordinates3906174..3907007
Orientation-
Molecular mass29397.5
Isoelectric point7.67

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3487c-925[no data]
JHU3487c-34[no data]
JHU3487c-696[no data]
JHU3487c-983[no data]
JHU3487c-18Not-Attenuated
JHU3487c-19[no data]
 

CDC1551 Homolog
ORFMT3591
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3487c-925MT3591Rv3487c925984yes
JHU3487c-696MT3591Rv3487c696984yes
JHU3487c-983MT3591Rv3487c983984yes
JHU3487c-19MT3591Rv3487c19984yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]