TARGET Research Results
Details
DescriptionCONSERVED HYPOTHETICAL PROLINE AND ALANINE RICH PROTEIN
Accession numberRv3876
Gene nameRv3876
Gene length2001
Protein length666
Coordinates4353010..4355010
Orientation+
Molecular mass70644.91
Isoelectric point10.28

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3876-1934[no data]
JHU3876-1815[no data]
JHU3876-1934[no data]
 

CDC1551 Homolog
ORFMT3990
Essentiality Prediction
Sassetti et al, 2003*[no data]

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3876-1934MT3990Rv387619342001yes
JHU3876-1815MT3990Rv387618152001yes
JHU3876-1934MT3990Rv387619342001yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]