Disclaimer: You are now leaving www.beiresources.org and are going to a website that is not operated by BEI Resources. We are not responsible for the content or availability of linked sites.
ABOUT THIRD PARTY LINKS ON OUR SITE: BEI Resources offers links to other third party websites that may be of interest to our website visitors. The links provided in our website are provided solely for your convenience and may assist you in locating other useful information on the Internet. When you click on these links, you will leave the BEI Resources website and will be redirected to another site. These sites are not under the control of BEI Resources. BEI Resources is not responsible for the content of linked third party websites. We are neither an agent for these third parties nor do we endorse or guarantee their products. We make no representation or warranty regarding the accuracy of the information contained in the linked sites. We suggest that you always verify the information obtained from linked websites before acting upon this information. Please read third party privacy and security policies closely as these may be different than BEI Resources policies. If you have any questions or concerns about the products and services offered on linked third party websites, please contact the third party directly.
This archive contains 224 antisera including antisera to many of the viruses listed and available for study. It contains, also, antisera to viruses no longer in our possession or found to be non-viable that are not listed in the Archive. Some of the properties of the antisera bearing F designations can be inferred by reference to the file (F) numbers of the immunizing viruses. For example, antiserum to an antigenically hybrid virus will also be hybrid with respect to its ability to recognize either HA or NA antigens of either of the two parental viruses.
Virtually all the antisera listed were produced by intravenous injection of New Zealand rabbits with virus in the form (usually) of gradient purified allantoic fluid virus or (less frequently) semi-purified allantoic fluid from chick embryos. These sera are "hyper-immune" in the sense that they represent secondary response antisera to a second (boosting) i.v. injection of virus administered approximately 40 days after the initial priming dose of virus. The sera listed here are final bleedings obtained 47-61 days after initial priming injections and 7 to 14 days after boost. They are polyclonal and polyvalent in the sense that they are reactive with both HA and NA envelope antigens of the virus. Those made to viral HA/NA antigenic hybrids can be used as HA or NA-specific reagents when immunization has been carried out with antigenically hybrid reassortant viruses in which either the HA or NA antigen is alien to human experience and therefore not significantly cross-reactive in tests in which response to one or the other antigens is measured in subjects previously primed to both by natural infection or vaccination.