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 The SARS-CoV-2 Variant-of-Concern Omicron, also referred to as B.1.1.529, remains the dominant variant currently circulating globally, with subvariant BA.2.12.1 rapidly spreading in the United States.1,2,3,4 Omicron variant isolates representing BA.1 and BA.2 sub-lineages are now available in the BEI Resources catalog, with several others in production such as BA.2.12.1 and BA.4.
Other interesting variants, an XD isolate from France containing markers of both Delta (AY.4 lineage) and Omicron variants resulting from multiple recombination events and a B.1.640.2 isolate, will also be made available shortly.5,6 In addition to the isolates, two SARS-CoV-2 spike (S) glycoproteins from Omicron lineages B.1.1.529 (NR-56447) and AY.4 (NR-56517), as well as a genomic RNA from lineage B.1.1.529 (NR-56494), are available for order.
A full, up-to-date listing of all currently available and upcoming SARS-CoV-2 isolates and proteins, as well as genomic RNA, monoclonal antibodies, plasmids, peptide arrays and inactivated virus preparations, is available on the newly updated SARS-CoV-2 resource page on the BEI Resources website. New features include a SARS-CoV-2 search category with variant and lineage filters and a New Released Reagents section listing all of the most recent SARS-CoV-2 items. The BEI Resources Knowledge Base now incorporates the SARS-CoV-2 Frequently Asked Questions on topics related to the ordering process and how to register. Please visit the BEI Resources website and take a look around.
For questions or help navigating the new features, please contact BEI Resources Customer Care at Contact@BEIResources.org
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BEI Resources
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Recently Added SARS-CoV-2 Isolates & Reagents
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NR-56447
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S Glycoprotein (Stabilized) from SARS-CoV-2, B.1.1.529 Lineage (Omicron Variant) with C-Terminal Histidine and Avi Tags, Recombinant from HEK293 Cells
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NR-56461
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Isolate hCoV-19/USA/MD-HP20874/2021 (Omicron Variant)
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NR-56481
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Isolate hCoV-19/USA/GA-EHC-2811C/2021 (Omicron Variant)
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NR-56494
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Genomic RNA from hCoV-19/USA/GA-EHC-2811C/2021 (Omicron Variant)
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NR-56495
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Isolate hCoV-19/USA/GA-EHC-2811C/2021 (Omicron Variant), Heat Inactivated
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NR-56517
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S Glycoprotein (Stabilized) from SARS-CoV-2, BA.2 Lineage (Omicron Variant) with C-Terminal Histidine and Avi Tags, Recombinant from HEK293 Cells
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NR-56520
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Isolate hCoV-19/USA/CO-CDPHE-2102544747/2021 (Lineage B.1.1.529, BA.2; Omicron Variant)
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References:
- “Covid Data Tracker.” Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, https://covid.cdc.gov/covid-data-tracker/#variant-proportions. Accessed 16 May 2022.
- "Science Brief: Omicron (B.1.1.529) Variant." Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, https://www.cdc.gov/coronavirus/2019-ncov/science/science-briefs/scientific-brief-omicron-variant.html. Accessed 16 May 2022.
- "SARS-CoV-2 Variant Classifications and Definitions." Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, https://www.cdc.gov/coronavirus/2019-ncov/variants/variant-classifications.html. Accessed 16 May 2022.
- "Omicron Variant Report." Outbreak.info, https://outbreak.info/situation-reports/omicron. Accessed 16 May 2022.
- Ou, S., et al. “Tracking SARS-CoV-2 Omicron Diverse Spike Gene Mutations Identifies Multiple Inter-Variant Recombination Events.” Signal Transduct. Target Ther. 7 (2022): 138. PubMed: 35474215.
- Moisan, A., et al. “Evidence of Transmission and Circulation of Deltacron XD Recombinant SARS-CoV-2 in Northwest France.” Clin. Infect. Dis. (2022): ciac360. Online Ahead of Print. PubMed: 35535770.
Image: Scanning electron micrograph image of SARS-CoV-2 emerging from the surface of a cell (NIAID/CC BY 2.0)
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