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NR-3481   Influenza A Virus, Kilbourne F28: A/turkey/Kansas/4880/1980 (HA, NA) x A/Puerto Rico/8/1934 (H1N1), Low (L) Yield
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Description: Influenza A Virus, Kilbourne F28: A/turkey/Kansas/4880/1980 (HA, NA) x A/Puerto Rico/8/1934 (H1N1), Low (L) Yield
Organism: Influenza A virus
Biosafety Level: 2
Availability Status: In Stock
Store at: -60°C or colder
Contributor: NIAID/NIH
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

The donor of the hemagglutinin and neuraminidase genes of NR-3481 is a low (L) yield derivative (Kilbourne F25; BEI Resources NR-3469) of influenza A virus, A/turkey/Kansas/4880/1980 (H1N1), which is a virus of swine antigenic phenotype isolated from a turkey in the course of a natural epizootic. As was the case with human isolates of swine phenotype, low- (L) and high-yield (H) HA mutants could be isolated from the wild type parent with the use of selective antibody. The other parent of this reassortant, X-31 (Kilbourne F108; BEI Resources NR-3483) is A/Aichi/2/1968 (HA, NA) x A/Puerto Rico/8/1934 (H3N2), and has been shown to contain only the HA and NA genes from A/Aichi/2/1968 (H3N2). Since these were replaced by the HA and NA genes of the A/turkey/Kansas/4880/1980 (H1N1), Low (L) Yield parent, NR-3481 does not contain any genes from A/Aichi/2/1968 (H3N2).

Each vial contains approximately 1 mL of pooled allantoic fluid from specific pathogen free (SPF) embryonated chicken eggs infected with reassortant influenza A virus, A/turkey/Kansas/4880/1980 (HA, NA) x A/Puerto Rico/8/1934 (H1N1), Low (L) Yield.

Kilbourne Archive Homepage
Kilbourne/New York Medical College Archive of Influenza Virus Reassortants and Mutants
Kilbourne F28 information
Download (Word Docs):Detailed Description
File Number:F28
Virus Name:
Virus Attributes:Type A Virus. A subtypes other than human. reassortant. human HA-specific antigenic hybrid . high yield reassortants
AntiserumImmunizing VirusLocationAntiserum Attributes
Citations: Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Kilbourne F28: A/turkey/Kansas/4880/1980 (HA, NA) x A/Puerto Rico/8/1934 (H1N1), Low (L) Yield, NR-3481."
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  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
  • USDA APHIS VS 16-6 or 16-6A permit must be obtained and a copy of the permit must be sent to ATCC in advance of shipment. The Application Form VS 16-3 (Import controlled material import or transport organisms or vectors) must be submitted to USDA APHIS Veterinary Services to obtain the VS 16-6 or 16-6A permit.

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