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BEI Resources currently limits the total number of "Made to Order" items which can be ordered by a registrant to 10 "Made to Order" items per 6 month period. Please check the Availability Status on the items you are ordering and limit orders appropriately.
NR-643  Francisella tularensis subsp. tularensis, SCHU S4 (FSC237)
Price: All BEI Resources products are provided
at no cost to registered researchers.
Organism: Francisella tularensis subsp. tularensis
Designations: SCHU S4 (FSC237)
Biosafety Level: 3
Availability Status: In Stock
Store at: -60°C or colder
Contributor: ME Schriefer
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

Francisella. tularensis subsp. tularensis, strain SCHU S4 was derived from an isolate obtained from a human case of tularemia in Ohio, USA.

The complete genome sequence of NR-643 is available (GenBank: JIDU01000000).

NR-643 has been confirmed as subspecies tularensis (Type A) by PCR amplification of a subspecies-specific sequence of approximately 390 base pairs from extracted DNA.

Each vial contains approximately 0.5 mL of bacterial culture in Mueller Hinton broth supplemented with 10% glycerol.
Citations: Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Francisella tularensis subsp. tularensis, Strain SCHU S4 (FSC237), NR-643."
Publications Citing
this Reagent:
Barrigan, L. M., et al. "Infection with Francisella tularensis LVS clpB Leads to an Altered yet Protective Immune Response." Infect. Immun. 81 (2013): 2028-2042. PubMed: 23529616.

Barrow, E. W., et al. "High-Throughput Screening of a Diversity Collection Using Biodefense Category A and B Priority Pathogens." J. Biomolec. Screen. 17 (2012): 946-956. PubMed: 22653912.

Brown, M. J., et al. "The Contribution of the Glycine Cleavage System to the Pathogenesis of Francisella tularensis." Microbes Infect. 16 (2013): 300-309. PubMed: 24374051.

Conlan, J. W., et al. "Infection of Mice with Francisella as an Immunological Model." Curr. Protoc. Immunol. 19 (2011). PubMed: 21462168.

Dotson, R. J., et al. "Repression of Inflammasome by Francisella tularensis During Early Stages of Infection." Biol. Chem. 288 (2013): 23844-23857. PubMed: 23821549.

Duncan, D., et al. "Identification and Typing of Francisella tularensis with a Highly Automated Genotyping Assay." Lett. Appl. Microbiol. 56 (2013): 128-134. PubMed: 23121644.

Emery, F. D., et al. "Efficient Inactivation of Burkholderia pseudomallei or Francisella tularensis in Infected Cells for Safe Removal from Biosafety Level 3 Containment Laboratories." Pathog. Dis. (2014): doi: 10.1111/2049-632X.12138. PubMed: 24449562.

Faith, S. A., et al. "Growth Conditions and Environmental Factors Impact Aerosolization but Not Virulence of Francisella tularensis Infection in Mice." Front. Cell. Infect. Microbiol. 2 (2012): doi: 10.3389. PubMed: 23087911.

Gregory, S. H., et al. "Detoxified Endotoxin Vaccine (J5dLPS/OMP) Protects Mice Against Lethal Respiratory Challenge with Francisella tularensis SchuS4." Vaccine 28 (2010): 2908-2915. PubMed: 20170768.

Li, Y., et al. "A Rapid One-Step Method for the Characterization of Membrane Lipid Remodeling in Francisella Using Matrix-Assisted Laser Desorption Ionization Time-of-Flight Tandem Mass Spectrometry." Rapid Commun. Mass Spectrom. 25 (2011): 2641-2648. PubMed: 23657959.

Lu, Z., et al. "Protective B-Cell Epitopes of Francisella tularensis O-Polysaccharide in a Mouse Model of Respiratory Tularaemia." Immunol. 136 (2012): 352-360. PubMed: 22486311.

Lu, Z., et al. "B-Cell Epitopes in GroEL of Francisella tularensis." PloS One 9 (2014): e99847. PubMed: 24968190.

Mahawar, M., et al. "Identification of a Live Attenuated Vaccine Candidate for Tularemia Prophylaxis." PloS One 8 (2013): e61539. PubMed: 23613871.

Mortensen, B. L., et al. "Effects of the Putative Transcriptional Regulator IclR on Francisella tularensis Pathogenesis." Infect. Immun. 78 (2010): 5022-5032. PubMed: 20921148.

Petersen, J. M. and C. R. Molins. "Subpopulations of Francisella tularensis ssp. tularensis and holarctica: Identification and Associated Epidemiology." Future Microbiol. 5 (2010): 649-661. PubMed: 20353304.

Pflughoeft, K. (2010). "The Immune Inhibitor A1 Protease of Bacillus anthracis."

Riojas, M.A., et al. "Multiplex PCR for Species-Level Identification of Bacillus anthracis and Detection of pXO1, pXO2, and Related Plasmids." Health Secur. 13 (2015): 122-129. PubMed: 25813976.

Roberts, L. M., et al. "Identification of Early Interactions Between Francisella and the Host." Inf. Imm. 82 (2014): 2504-2510. PubMed: 24686053.

Roche, M. I., et al. "Characterization of Monoclonal Antibodies to Terminal and Internal O-Antigen Epitopes of Francisella tularensis Lipopolysaccharide." Hybridoma 30 (2011): 19-28. PubMed: 21466282.

Valentino, M. D., et al. "Identification of T-Cell Epitopes in Francisella tularensis Using an Ordered Protein Array of Serological Targets." Immunol. 132 (2011): 348-360. PubMed: 21214540.

Wang, Q., et al. "A Typical Preparation of Francisella tularensis O-Antigen Yields a Mixture of Three Types of Saccharides." Biochem. 50 (2011): 10941-10950. PubMed: 22091710.

Zinman, G., et al. "Large Scale Comparison of Innate Responses to Viral and Bacterial Pathogens in Mouse and Macaque." PloS One 6 (2011): e22401. PubMed: 21789257.
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Genomic DNA from Francisella tularensis subsp. tularensis, Strain SCHU S4 (FSC237)
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