TARGET Research Results
Details
DescriptionPE FAMILY PROTEIN
Accession numberRv0151c
Gene namePE1
Gene length1767
Protein length588
Coordinates177543..179309
Orientation-
Molecular mass61411.23
Isoelectric point4.13

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU0151c-1127[no data]
JHU0151c-1126[no data]
JHU0151c-458[no data]
JHU0151c-1127[no data]
JHU0151c-1738[no data]
JHU0151c-84Not-Attenuated
JHU0151c-1126[no data]
JHU0151c-1076[no data]
JHU0151c-903[no data]
 

CDC1551 Homolog
ORFMT0160
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU0151c-1127MT0160Rv0151c11271767no (will be available later)
JHU0151c-1126MT0160Rv0151c11261767no (will be available later)
JHU0151c-458MT0160Rv0151c4581767yes
JHU0151c-1127MT0160Rv0151c11271767yes
JHU0151c-1738MT0160Rv0151c17381767no (will be available later)
JHU0151c-1126MT0160Rv0151c11261767no (will be available later)
JHU0151c-1076MT0160Rv0151c10761767no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]