TARGET Research Results
DescriptionProbable polyketide synthase pks12
Accession numberRv2048c
Gene namepks12
Gene length12456
Protein length4151
Molecular mass431580.06
Isoelectric point4.86

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig


Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2048c-7552[no data]
JHU2048c-2248[no data]
JHU2048c-4625[no data]
JHU2048c-6631[no data]

CDC1551 Homolog
Essentiality Prediction
Sassetti et al, 2003*[no data]

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2048c-7552MT2108Rv2048c755212456no (will be available later)
JHU2048c-4625MT2108Rv2048c462512456no (will be available later)
JHU2048c-6631MT2108Rv2048c663112456no (will be available later)
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]