TARGET Research Results
Details
DescriptionPOSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
Accession numberRv2077c
Gene nameRv2077c
Gene length972
Protein length323
Coordinates2333323..2334294
Orientation-
Molecular mass33321.18
Isoelectric point4.83

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2077c-422[no data]
JHU2077c-284[no data]
JHU2077c-386[no data]
 

CDC1551 Homolog
ORFMT2137
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2077c-422MT2137Rv2077c422972no (will be available later)
JHU2077c-284MT2137Rv2077c284972no (will be available later)
JHU2077c-386MT2137Rv2077c386972yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]