TARGET Research Results
Details
DescriptionHYPOTHETICAL PROTEIN
Accession numberRv2114
Gene nameRv2114
Gene length624
Protein length207
Coordinates2373834..2374457
Orientation+
Molecular mass22774.64
Isoelectric point4.81

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2114-561[no data]
JHU2114-556[no data]
JHU2114-101[no data]
JHU2114-367[no data]
JHU2114-554[no data]
 

CDC1551 Homolog
ORFMT2174
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2114-556MT2174Rv2114556663yes
JHU2114-101MT2174Rv2114101663yes
JHU2114-367MT2174Rv2114367663no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]