TARGET Research Results
Details
DescriptionProbable conserved integral membrane protein
Accession numberRv2180c
Gene nameRv2180c
Gene length888
Protein length295
Coordinates2442327..2443214
Orientation-
Molecular mass33195.13
Isoelectric point10.83

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2180c-27[no data]
JHU2180c-762[no data]
JHU2180c-386[no data]
JHU2180c-495[no data]
 

CDC1551 Homolog
ORFMT2235
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2180c-27MT2235Rv2180c27939yes
JHU2180c-762MT2235Rv2180c762939no (will be available later)
JHU2180c-386MT2235Rv2180c386939yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]