TARGET Research Results
Details
DescriptionPROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
Accession numberRv2723
Gene nameRv2723
Gene length1194
Protein length397
Coordinates3034909..3036102
Orientation+
Molecular mass43679.27
Isoelectric point8.91

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2723-538[no data]
JHU2723-499[no data]
JHU2723-420[no data]
JHU2723-769[no data]
 

CDC1551 Homolog
ORFMT2795
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2723-538MT2795Rv27235381194yes
JHU2723-499MT2795Rv27234991194yes
JHU2723-420MT2795Rv27234201194yes
JHU2723-769MT2795Rv27237691194no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]