TARGET Research Results
Details
DescriptionHYPOTHETICAL PROTEIN
Accession numberRv2730
Gene nameRv2730
Gene length477
Protein length158
Coordinates3042542..3043018
Orientation+
Molecular mass16476.41
Isoelectric point10.76

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2730-239Moderately-attenauated
JHU2730-472[no data]
JHU2730-237[no data]
JHU2730-471[no data]
 

CDC1551 Homolog
ORFMT2801.1
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2730-472MT2801.1Rv2730472477yes
JHU2730-237MT2801.1Rv2730237477no (will be available later)
JHU2730-471MT2801.1Rv2730471477yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]