TARGET Research Results
Details
DescriptionCONSERVED HYPOTHETICAL PROTEIN
Accession numberRv2797c
Gene nameRv2797c
Gene length1689
Protein length562
Coordinates3105619..3107307
Orientation-
Molecular mass58759.39
Isoelectric point4.65

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2797c-1165[no data]
JHU2797c-287[no data]
JHU2797c-637Not-Attenuated
JHU2797c-1499[no data]
JHU2797c-1343[no data]
 

CDC1551 Homolog
ORFMT2866
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2797c-1165MT2866Rv2797c11651689yes
JHU2797c-287MT2866Rv2797c2871689no (will be available later)
JHU2797c-1499MT2866Rv2797c14991689no (will be available later)
JHU2797c-1343MT2866Rv2797c13431689yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]