TARGET Research Results
Details
DescriptionPROBABLE INTEGRAL MEMBRANE PROTEIN
Accession numberRv3481c
Gene nameRv3481c
Gene length690
Protein length229
Coordinates3900493..3901182
Orientation-
Molecular mass23793.31
Isoelectric point10.54

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3481c-551[no data]
JHU3481c-116[no data]
JHU3481c-594[no data]
 

CDC1551 Homolog
ORFMT3585
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3481c-551MT3585Rv3481c551690yes
JHU3481c-116MT3585Rv3481c116690yes
JHU3481c-594MT3585Rv3481c594690no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]