TARGET Research Results
Details
DescriptionPOSSIBLE SIDEROPHORE-BINDING PROTEIN
Accession numberRv3525c
Gene nameRv3525c
Gene length525
Protein length174
Coordinates3961800..3962324
Orientation-
Molecular mass17665.39
Isoelectric point5.89

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3525c-323[no data]
JHU3525c-522[no data]
JHU3525c-139Not-Attenuated
JHU3525c-459[no data]
 

CDC1551 Homolog
ORFMT3625
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3525c-522MT3625Rv3525c522525yes
JHU3525c-459MT3625Rv3525c459525no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]