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NR-20083   Influenza A (H1N1) 2009 Monovalent Vaccine
(Vaccines)
Price: All BEI Resources products are provided
at no cost to registered researchers.
Description: Influenza A (H1N1) 2009 Monovalent Vaccine
Organism: Influenza A virus
Biosafety Level: 1
Availability Status: In Stock
Store at: 2°C to 8°C
Contributor: NIAID/NIH
Comments:
Quantity limit per order for this item is 3. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

Influenza A (H1N1) 2009 (pdm09) Monovalent Vaccine is a subunit (purified surface antigen) influenza virus vaccine prepared from A/California/7/2009 (H1N1)pdm09-like virus propagated in the allantoic cavity of embryonated chicken eggs. The virus was harvested and clarified by centrifugation and filtration prior to inactivation with betapropiolactone. The inactivated virus was concentrated and purified by zonal centrifugation. The surface antigens, hemagglutinin and neuraminidase, were obtained from the influenza virus particle by further centrifugation in the presence of nonylphenol ethoxylate, a process which removes most of the internal proteins. The nonylphenol ethoxylate was removed from the surface antigen preparation. Thimerosal, a mercury derivative used during manufacture, was removed by the purification steps to a trace amount (≤ 1 µg mercury per dose). Each 0.5 mL dose may also contain residual amounts of egg proteins (≤ 1 µg ovalbumin), polymyxin (≤ 3.75 µg), neomycin (≤ 2.5 µg), betapropiolactone (≤ 0.5 µg) and nonylphenol ethoxylate (≤ 0.015% w/v).

The hemagglutinin content was standardized according to U.S. Public Health Service requirements. Each 0.5 mL syringe contains the recommended 15 µg of hemagglutinin antigen.

Please note that this vaccine preparation is being released for research use only and not for human use. Vaccines produced for the 2009-2010 season are now past their expiration dates.

Each syringe contains 0.5 mL of monovalent vaccine in phosphate-buffered saline.
Citations: Acknowledgment for publications should read "The following reagent was obtained through BEI Resources Repository, NIAID, NIH: Influenza A (H1N1) 2009 Monovalent Vaccine, NR-20083."
Publications Citing
this Reagent:
Weaver, E. A. and M. A. Barry. "Low Seroprevalent Species D Adenovirus Vectors as Influenza Vaccines." PloS one 8 (2013): e73313. PubMed: 23991187
PERMITS
For a list of permits that may be required for shipping this product and to set the permit information preferences; please select a country from the drop down below.

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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