TARGET Research Results
Details
DescriptionPOSSIBLE LIPOPROTEIN LPRO
Accession numberRv0179c
Gene namelprO
Gene length1110
Protein length369
Coordinates209703..210812
Orientation-
Molecular mass39160.15
Isoelectric point8.99

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU0179c-853[no data]
JHU0179c-679[no data]
JHU0179c-1109[no data]
 

CDC1551 Homolog
ORFMT0188
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU0179c-853MT0188Rv0179c8531110no (will be available later)
JHU0179c-679MT0188Rv0179c6791110yes
JHU0179c-1109MT0188Rv0179c11091110no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]