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TARGET Research Results
Details
DescriptionPPE FAMILY PROTEIN
Accession numberRv0355c
Gene namePPE8
Gene length9903
Protein length3300
Coordinates424777..434679
Orientation-
Molecular mass327030.06
Isoelectric point3.93

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU0355c-9632[no data]
JHU0355c-2254[no data]
JHU0355c-1106[no data]
JHU0355c-9602[no data]
JHU0355c-5053[no data]
JHU0355c-6366[no data]
JHU0355c-5053[no data]
JHU0355c-4588[no data]
JHU0355c-8878[no data]
JHU0355c-5991[no data]
123
 

CDC1551 Homolog
ORFMT0370
Essentiality Prediction
Sassetti et al, 2003*[no data]

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU0355c-9632MT0370Rv0355c96329828no (will be available later)
JHU0355c-2254MT0370Rv0355c22549828yes
JHU0355c-1106MT0370Rv0355c11069828yes
JHU0355c-9602MT0370Rv0355c96029828no (will be available later)
JHU0355c-5053MT0370Rv0355c50539828no (will be available later)
JHU0355c-6366MT0370Rv0355c63669828no (will be available later)
JHU0355c-5053MT0370Rv0355c50539828yes
JHU0355c-4588MT0370Rv0355c45889828yes
JHU0355c-8878MT0370Rv0355c88789828no (will be available later)
JHU0355c-5991MT0370Rv0355c59919828no (will be available later)
JHU0355c-8233MT0370Rv0355c82339828no (will be available later)
JHU0355c-6879MT0370Rv0355c68799828no (will be available later)
JHU0355c-4350MT0370Rv0355c43509828no (will be available later)
JHU0355c-8317MT0370Rv0355c83179828no (will be available later)
JHU0355c-3587MT0370Rv0355c35879828no (will be available later)
JHU0355c-9632MT0370Rv0355c96329828no (will be available later)
JHU0355c-3241MT0370Rv0355c32419828yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]
 
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