TARGET Research Results
Details
DescriptionPROBABLE TRANSCRIPTION-REPAIR COUPLING FACTOR MFD (TRCF)
Accession numberRv1020
Gene namemfd
Gene length3705
Protein length1234
Coordinates1138967..1142671
Orientation+
Molecular mass132908.05
Isoelectric point5.6

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1020-3208[no data]
JHU1020-3067[no data]
JHU1020-3067[no data]
JHU1020-2812[no data]
 

CDC1551 Homolog
ORFMT1048
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1020-3208MT1048Rv102032083705yes
JHU1020-3067MT1048Rv102030673705yes
JHU1020-3067MT1048Rv102030673705no (will be available later)
JHU1020-2812MT1048Rv102028123705yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]