TARGET Research Results
Details
DescriptionTWO COMPONENT TRANSCRIPTIONAL REGULATOR TRCR
Accession numberRv1033c
Gene nametrcR
Gene length774
Protein length257
Coordinates1157963..1158736
Orientation-
Molecular mass29209.36
Isoelectric point6.06

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1033c-737[no data]
JHU1033c-736[no data]
JHU1033c-214Not-Attenuated
JHU1033c-556[no data]
 

CDC1551 Homolog
ORFMT1062
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1033c-736MT1062Rv1033c736831yes
JHU1033c-556MT1062Rv1033c556831yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]