TARGET Research Results
Details
DescriptionPROBABLE MEMBRANE PROTEIN
Accession numberRv1231c
Gene nameRv1231c
Gene length543
Protein length180
Coordinates1374322..1374864
Orientation-
Molecular mass20413.28
Isoelectric point9.92

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1231c-254[no data]
JHU1231c-421[no data]
JHU1231c-31[no data]
JHU1231c-421[no data]
JHU1231c-209[no data]
 

CDC1551 Homolog
ORFMT1269
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1231c-254MT1269Rv1231c254543yes
JHU1231c-421MT1269Rv1231c421543no (will be available later)
JHU1231c-421MT1269Rv1231c421543no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]