TARGET Research Results
Details
DescriptionHYPOTHETICAL PROTEIN
Accession numberRv1724c
Gene nameRv1724c
Gene length420
Protein length139
Coordinates1950632..1951051
Orientation-
Molecular mass16229.41
Isoelectric point8.21

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1724c-302[no data]
JHU1724c-300Not-Attenuated
JHU1724c-232[no data]
JHU1724c-231[no data]
 

CDC1551 Homolog
ORFMT1765
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1724c-302MT1765Rv1724c302420yes
JHU1724c-232MT1765Rv1724c232420no (will be available later)
JHU1724c-231MT1765Rv1724c231420yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]