TARGET Research Results
Details
DescriptionPROBABLE OXIDOREDUCTASE
Accession numberRv1774
Gene nameRv1774
Gene length1341
Protein length446
Coordinates2007832..2009172
Orientation+
Molecular mass48340.46
Isoelectric point5.23

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1774-632[no data]
JHU1774-1084[no data]
JHU1774-875[no data]
JHU1774-1153[no data]
 

CDC1551 Homolog
ORFMT1824
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1774-632MT1824Rv17746321341yes
JHU1774-1084MT1824Rv177410841341no (will be available later)
JHU1774-875MT1824Rv17748751341no (will be available later)
JHU1774-1153MT1824Rv177411531341no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]