TARGET Research Results
Details
DescriptionCONSERVED HYPOTHETICAL PROTEIN
Accession numberRv1798
Gene nameRv1798
Gene length1833
Protein length610
Coordinates2036700..2038532
Orientation+
Molecular mass67755.87
Isoelectric point5.15

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1798-1562[no data]
JHU1798-324[no data]
JHU1798-305[no data]
JHU1798-1340[no data]
JHU1798-331Attenuated
 

CDC1551 Homolog
ORFMT1847
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1798-1562MT1847Rv179815621833yes
JHU1798-324MT1847Rv17983241833no (will be available later)
JHU1798-305MT1847Rv17983051833yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]