TARGET Research Results
Details
DescriptionPROBABLE SIALIC ACID-TRANSPORT INTEGRAL MEMBRANE PROTEIN NANT
Accession numberRv1902c
Gene namenanT
Gene length1269
Protein length422
Coordinates2149006..2150274
Orientation-
Molecular mass46420.49
Isoelectric point9.87

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1902c-390Not-Attenuated
JHU1902c-629[no data]
JHU1902c-706[no data]
JHU1902c-760[no data]
 

CDC1551 Homolog
ORFMT1953
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1902c-629MT1953Rv1902c6291227yes
JHU1902c-706MT1953Rv1902c7061227yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]