TARGET Research Results
Details
DescriptionCONSERVED HYPOTHETICAL PROTEIN
Accession numberRv2411c
Gene nameRv2411c
Gene length1656
Protein length551
Coordinates2708310..2709965
Orientation-
Molecular mass61383.18
Isoelectric point5.55

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2411c-590Not-Attenuated
JHU2411c-161[no data]
JHU2411c-100[no data]
JHU2411c-101[no data]
JHU2411c-851[no data]
JHU2411c-589[no data]
 

CDC1551 Homolog
ORFMT2484
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2411c-100MT2484Rv2411c1001656yes
JHU2411c-101MT2484Rv2411c1011656yes
JHU2411c-851MT2484Rv2411c8511656no (will be available later)
JHU2411c-589MT2484Rv2411c5891656no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]