TARGET Research Results
Details
DescriptionPROBABLE CONSERVED LIPOPROTEIN LPPS
Accession numberRv2518c
Gene namelppS
Gene length1227
Protein length409
Coordinates2834109..2835335
Orientation-
Molecular mass43365.8
Isoelectric point6.52

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2518c-872[no data]
JHU2518c-875[no data]
JHU2518c-358[no data]
JHU2518c-874[no data]
 

CDC1551 Homolog
ORFMT2594
Essentiality Prediction
Sassetti et al, 2003*[no data]

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2518c-872MT2594Rv2518c8721227no (will be available later)
JHU2518c-875MT2594Rv2518c8751227no (will be available later)
JHU2518c-358MT2594Rv2518c3581227no (will be available later)
JHU2518c-874MT2594Rv2518c8741227no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]