TARGET Research Results
Details
DescriptionPE-PGRS FAMILY PROTEIN
Accession numberRv2634c
Gene namePE_PGRS46
Gene length2337
Protein length778
Coordinates2960105..2962441
Orientation-
Molecular mass63130.42
Isoelectric point3.6

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU2634c-345[no data]
JHU2634c-290[no data]
JHU2634c-203[no data]
 

CDC1551 Homolog
ORFMT2712
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU2634c-345MT2712Rv2634c3452367no (will be available later)
JHU2634c-290MT2712Rv2634c2902367yes
JHU2634c-203MT2712Rv2634c2032367yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]