TARGET Research Results
Details
DescriptionPPE FAMILY PROTEIN
Accession numberRv3018c
Gene namePPE46
Gene length1305
Protein length434
Coordinates3376939..3378243
Orientation-
Molecular mass42997.26
Isoelectric point3.82

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3018c-223[no data]
JHU3021c-223[no data]
JHU3022c-223[no data]
 

CDC1551 Homolog
ORFMT3106
Essentiality Prediction
Sassetti et al, 2003*essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3018c-223MT3106Rv3018c2231308yes
JHU3021c-223MT3106Rv3021c2231308yes
JHU3022c-223MT3106Rv3022c2231308yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]