TARGET Research Results
Details
DescriptionPROBABLE ATP-DEPENDENT DNA HELICASE II UVRD2
Accession numberRv3198c
Gene nameuvrD2
Gene length2103
Protein length700
Coordinates3569109..3571211
Orientation-
Molecular mass75603.47
Isoelectric point6.96

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3198c-2000[no data]
JHU3198c-1954[no data]
JHU3198c-1115[no data]
 

CDC1551 Homolog
ORFMT3291
Essentiality Prediction
Sassetti et al, 2003*essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3198c-1954MT3291Rv3198c19542103yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]