TARGET Research Results
Details
DescriptionPROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
Accession numberRv3295
Gene nameRv3295
Gene length666
Protein length221
Coordinates3676066..3676731
Orientation+
Molecular mass24805.25
Isoelectric point5.18

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3295-288[no data]
JHU3295-155[no data]
JHU3295-286[no data]
JHU3295-451[no data]
 

CDC1551 Homolog
ORFMT3394
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3295-288MT3394Rv3295288666yes
JHU3295-155MT3394Rv3295155666yes
JHU3295-286MT3394Rv3295286666no (will be available later)
JHU3295-451MT3394Rv3295451666yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]