TARGET Research Results
Details
DescriptionCHOLESTEROL OXIDASE CHOD (CHOLESTEROL-O2 OXIDOREDUCTASE)
Accession numberRv3409c
Gene namechoD
Gene length1737
Protein length578
Coordinates3826991..3828727
Orientation-
Molecular mass63023.64
Isoelectric point9.67

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3409c-1477[no data]
JHU3409c-1495Not-Attenuated
JHU3409c-201[no data]
 

CDC1551 Homolog
ORFMT3517
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3409c-1477MT3517Rv3409c14771737yes
JHU3409c-201MT3517Rv3409c2011737yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]