TARGET Research Results
Details
DescriptionPOSSIBLE OXIDOREDUCTASE
Accession numberRv3553
Gene nameRv3553
Gene length1068
Protein length355
Coordinates3991621..3992688
Orientation+
Molecular mass36830.69
Isoelectric point9.86

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3553-1002[no data]
JHU3553-15[no data]
JHU3553-1056[no data]
 

CDC1551 Homolog
ORFMT3657
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3553-1002MT3657Rv355310021083yes
JHU3553-15MT3657Rv3553151083no (will be available later)
JHU3553-1056MT3657Rv355310561083no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]