TARGET Research Results
Details
DescriptionCONSERVED HYPOTHETICAL PROTEIN
Accession numberRv3719
Gene nameRv3719
Gene length1413
Protein length470
Coordinates4162306..4163718
Orientation+
Molecular mass53006.81
Isoelectric point7.55

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3719-755[no data]
JHU3719-815[no data]
JHU3719-18[no data]
 

CDC1551 Homolog
ORFMT3822
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3719-755MT3822Rv37197551401yes
JHU3719-815MT3822Rv37198151401no (will be available later)
JHU3719-18MT3822Rv3719181401yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]