TARGET Research Results
Details
DescriptionPOSSIBLE OXIDOREDUCTASE
Accession numberRv3727
Gene nameRv3727
Gene length1809
Protein length602
Coordinates4172955..4174763
Orientation+
Molecular mass66293.65
Isoelectric point8.65

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3727-146[no data]
JHU3727-431[no data]
JHU3727-1305[no data]
JHU3727-1535[no data]
 

CDC1551 Homolog
ORFMT3830
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3727-146MT3830Rv37271461809yes
JHU3727-431MT3830Rv37274311809yes
JHU3727-1305MT3830Rv372713051809yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]