TARGET Research Results
Details
DescriptionPROBABLE CONSERVED TWO-DOMAIN MEMBRANE PROTEIN
Accession numberRv3728
Gene nameRv3728
Gene length3198
Protein length1065
Coordinates4174873..4178070
Orientation+
Molecular mass111231.21
Isoelectric point10.6

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3728-2635[no data]
JHU3728-79[no data]
JHU3728-2757[no data]
 

CDC1551 Homolog
ORFMT3831
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3728-2635MT3831Rv372826353216yes
JHU3728-79MT3831Rv3728793216no (will be available later)
JHU3728-2757MT3831Rv372827573216yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]