TARGET Research Results
Details
DescriptionPOSSIBLE CONSERVED MEMBRANE PROTEIN
Accession numberRv3869
Gene nameRv3869
Gene length1443
Protein length480
Coordinates4345039..4346481
Orientation+
Molecular mass51092.58
Isoelectric point7.74

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU3869-836[no data]
JHU3869-1226[no data]
JHU3869-253[no data]
 

CDC1551 Homolog
ORFMT3982
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU3869-836MT3982Rv38698361443no (will be available later)
JHU3869-1226MT3982Rv386912261443yes
JHU3869-253MT3982Rv38692531443no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]