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BSL 2 Reporter Virus Particles for Vaccine & Antiviral Research
Reporter virus particles (RVPs) are non replicative, virus like particles engineered to display the authentic surface (envelope) proteins of pathogenic viruses while carrying a modified genome that cannot replicate. They are antigenically equivalent to live virus at the level of viral entry but are replication incompetent and safe to use at BSL 2, eliminating the need for high containment facilities or propagation of infectious virus. RVPs are optimized for infectivity and neutralization assays, including high throughput formats, and typically use Renilla luciferase (RLuc) or Green Fluorescent Protein (GFP) reporters for quantitative readouts. Built on established core systems such as lentivirus, VSV, or virus specific flavivirus platforms, RVPs provide a reliable, ready to use surrogate for closely modeling biologically relevant viral entry behavior. More information can be found here.
BEI Resources is now offering a variety of contemporary reporter virus particles to support in vaccine, antibody, and antiviral research into these high consequence pathogens.
Reporter Virus Particles
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BEI Item No.
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Description
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| NR-61710 |
Dengue Virus Type 1 (DENV-1) 16007 RVPs, RLuc |
| NR-61711 |
Dengue Virus Type 2 (DENV-2) 16681 RVPs, RLuc |
| NR-61712 |
Dengue Virus Type 3 (DENV-3) 16562 RVPs, RLuc – Coming Soon |
| NR-61713 |
Dengue Virus Type 4 (DENV-4) TVP360 RVPs, RLuc – Coming Soon |
| NR-61714 |
Human Coronavirus 229E (HCoV-229E) DQ243963.1 RVPs, RLuc |
| NR-61715 |
Human Coronavirus 229E (HCoV-229E) DQ243963.1, RVPs, GFP |
| NR-61716 |
Yellow Fever Virus (YFV) Asibi RVPs, RLuc |
| NR-61717 |
Yellow Fever Virus (YFV) 17D RVPs, RLuc |
| NR-61718 |
Nipah Virus Strain Malaysia 2008 RVPs, RLuc – Coming Soon |
| NR-61719 |
Nipah Virus Strain Malaysia 2008 RVPs, GFP – Coming Soon |
| NR-61720 |
O’nyong’nyong Virus (ONNV) Igbo Ora RVPs, GFP |
| NR-61721 |
Sindbis Virus (SINV) Species Exemplar RVPs, GFP |
References:
1. “Explore our High-Quality Virology Reagents.” Integral Molecular, https://virology.integralmolecular.com/product-information. Accessed 20 May 2026..
Image Alt Text: Dengue RVPs contain the native viral structural proteins envelope (E), and pre-membrane/membrane (prM/M) in a lipid envelope, capsid protein, and a reporter RNA replicon genome. Credit: Integral Molecular. (Integral Molecular/CC BY-SA 4.0)
Image Credit: Dengue RVPs (Integral Molecular/CC BY-SA 4.0)
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