Clostridium difficile research is easier with strains from BEI Resources
Clostridium difficile (also known as Peptoclostridium difficile) is an increasingly common opportunistic pathogen that causes diarrhea and more serious intestinal conditions such as colitis. It is commonly observed in patients that have an illness that requires prolonged use of antibiotics, or can be acquired in hospitals and long-term care facilities. C. difficile infections are normally treated with antibiotics; however, this is particularly problematic due to the high levels of antibiotic resistance displayed by these bacteria. Recent studies have shown that replenishment of the normal gut microbiota provides a successful tool to control the infection with C. difficile.
BEI Resources has a large number of C. difficile strains, as well as nucleic acids,
toxins, and other reagents available for your research (please click here for a list).
Among the bacterial strains, several have well characterized tcdA, tcdB, and cdtB toxin